Growth hormone improves short stature in children with Shwachman-Diamond syndrome
نویسندگان
چکیده
منابع مشابه
Growth Hormone in the Treatment of Children with Short Stature
Therapeutic use of growth hormone (GH) in the United States generally has been restricted to GHdeficient children who, with their families, agree to participate in research. The limited supply and the considerable expense of commercially prepared GH have restricted the number of children who have received such therapy. As the medical community and public become more aware of the therapeutic pot...
متن کاملGrowth hormone receptor mutations in children with idiopathic short stature.
Homozygous or compound heterozygous mutations in the GH receptor (GHR) gene result in GH insensitivity syndrome. Previous reports have shown that some heterozygous mutations may induce a partial insensitivity to GH, but others appear to have limited effect on growth. To investigate further these observations, we analyzed the GHR gene in 17 subjects with idiopathic short stature (ISS). All subje...
متن کاملGrowth Hormone in the Treatment of Children with Short Stature
Therapeutic use of growth hormone (GH) in the United States generally has been restricted to GHdeficient children who, with their families, agree to participate in research. The limited supply and the considerable expense of commercially prepared GH have restricted the number of children who have received such therapy. As the medical community and public become more aware of the therapeutic pot...
متن کاملGrowth Hormone in the Treatment of Children with Short Stature
Therapeutic use of growth hormone (GH) in the United States generally has been restricted to GHdeficient children who, with their families, agree to participate in research. The limited supply and the considerable expense of commercially prepared GH have restricted the number of children who have received such therapy. As the medical community and public become more aware of the therapeutic pot...
متن کاملGrowth hormone-induced nitrogen retention in children of short stature.
The decrease in urinary nitrogen excretion (i.e. increased nitrogen retention) following intramuscular injection of human growth hormone (HGH) has been used to differentiate hypopituitary dwarfism from other types of short stature. While small decreases can be demonstrated in almost all children who are given HGH, in the hypopituitary child the decrease is greater and more prolonged. Using a st...
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ژورنال
عنوان ژورنال: Pediatric Endocrinology Diabetes and Metabolism
سال: 2021
ISSN: 2081-237X
DOI: 10.5114/pedm.2021.105298